Monday, April 23, 2012

Aspartame

What is aspartame?
Aspartame is one of the most common artificial sweeteners in use today. Aspartame is composed mainly of 2 amino acids, aspartic acid and phenylalanine. Amino acids are the building blocks of proteins and are found naturally in many foods.
Aspartame is used in many foods and beverages because it is about 200 times sweeter than sugar, so much less of it can be used to give the same level of sweetness. This, in turn, lowers the calories in the food or beverage.
Rumors claiming that aspartame causes a number of health problems, including cancer, have been around for many years. Many of these continue to circulate on the Internet.
How are people exposed to aspartame?
Aspartame has been used in the United States since the early 1980s. It is now found in thousands of different food products. Aspartame is commonly used as a tabletop sweetener, as a sweetener in prepared foods and beverages, and in recipes that do not require too much heating (since heat breaks down aspartame).
How is aspartame regulated?
In the United States, artificial food sweeteners such as aspartame are regulated by the Food and Drug Administration (FDA). These products must be tested for safety and approved by the FDA before they can be used. The FDA also sets an acceptable daily intake (ADI) for each sweetener, which is the maximum amount considered safe to consume each day during a person’s lifetime. The ADI is set to be about 100 times less than the smallest amount that might cause health concerns, based on studies done in lab animals.
The FDA has set the ADI for aspartame at 50 milligrams per kilogram (mg/kg) of body weight. (In the European Union, the European Food Safety Authority has recommended a slightly lower ADI for aspartame, at 40 mg/kg.)
To put the ADI for aspartame in perspective, this would be 3,750 milligrams per day for a typical adult weighing 75 kilograms (about 165 pounds), far more than most adults take in daily. A can of diet soda usually contains about 180 milligrams of aspartame, so a typical adult would have to drink about 21 cans of diet soda a day to go over the recommended level.
Does aspartame cause cancer?
Researchers use 2 main types of studies to try to determine if a substance or exposure causes cancer. (A substance that causes cancer or helps cancer grow is called a carcinogen.)
In studies done in the lab, animals are exposed to a substance (often in very large doses) to see if it causes tumors or other health problems. It’s not always clear if the results from these types of studies will apply to humans, but lab studies are the best way to find out if a substance has the potential to cause cancer in humans before widespread exposure occurs.
Another type of study looks at cancer rates in different groups of people. Such a study might compare the cancer rate in a group exposed to a substance versus the rate in a group not exposed to it, or compare it to what the expected cancer rate would be in the general population. But studies in people can sometimes be hard to interpret, because there may be other factors affecting the results that are hard to account for.
In most cases neither type of study provides definitive evidence on its own, so researchers usually look at both lab-based and human studies if they are available.
Does aspartame cause any other health problems?
Complaints of various health issues have circulated since aspartame first appeared on the market in the 1980s. But for most people, no health problems have clearly been linked to aspartame(food additives) use.
Other health complaints
Claims have been made that aspartame is related to health effects ranging from mild problems such as headache, dizziness, digestive symptoms, and changes in mood, to more serious health issues such as Alzheimer disease, birth defects, diabetes, Gulf War syndrome, attention deficit disorders, Parkinson disease, lupus, multiple sclerosis, and seizures. However, studies done to date have not found any consistent evidence of harm. Research into the safety of aspartame continues.
Should I limit my exposure to aspartame?
Aside from the possible effects in people with phenylketonuria, there are no health problems that have been consistently linked to aspartame use. Research on artificial sweeteners, including aspartame, continues today.

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