Thursday, September 27, 2012

Cycle Of Citric Acid

Citrus acid cycle is a series of enzyme-catalyzed chemical reactions that occur as part of the cellular respiration. Precisely, it is the matrix exists in a cell's mitochondria. Its metabolic pathway, whereas the fuel generated using part of the body. Citric acid cycle, lift our body's energy source.

The major metabolic pathway in the Krebs cycle aerobic treatment in animal tissues. It was found in 1937, also known as the citric acid cycle or tricarboxylic acid cycle (TCA cycle). It is a series of living cells is an important reaction. They provide complete oxidation of C2 units or acetyl-CoA derived from fat, carbohydrates, and lipids. The oxidation method, gives the carbon dioxide and water.

Citrus acid cycle reaction
As mentioned earlier, citrus acid cycle is a complete breakdown of the food to produce energy from the energy-rich molecules, is in the final reaction product. Organism using the energy generated from these molecules as fuel. Acetyl coenzyme breakdown arising sugars, fatty acids and certain amino acids, oxaloacetate reaction to further produce a series of enzyme-catalyzed chemical reactions, it is again converted into oxaloacetate citrate. The chemical conversion treatment in the whole process, at different stages to produce carbon dioxide and water, and is also formed energy warehouse ATP molecule.

The steps involved in chemical reactions
Citric acid cycle, the beginning of the transfer of coenzyme A 2 - carbon acetyl 4 carbon compound oxalyl acetic acid, and a 6 is formed - carbon molecules citric.

Citrates, and then re-arranged to form the same in the form of isomers (the isomer is a molecule to another molecule, but has the same atomic number and type of the structure is different.) Therefore, the formation of an isocitrate.

6 - carbon isocitrate is then oxidized, and the resulting 5 - carbon molecules the α-ketuglutarate removing carbon dioxide molecules. In this process the oxidation of NAD is converted into NADH (equivalent to 3 of ATP) + H

Then, coenzyme A is deleted so that the succinic acid can be produced. The energy is released for causing guanosine diphosphate or GDP from triphosphate bird glycoside or GTP. GTP, and then converted to ADP.

Then, in the last step to generate the Succiante is converted into a oxidation of fumarate process. In this process, FAD reduced to FADH2.

Malate was added water is formed from fumaric acid. Then Malate after oxidation process, which is the starting compound of the Citric Acid Anhydrous cycle to produce oxaloacetate. Oxidation in this process, NAD + is reduced into NADH + H.

This cycle is often referred amphibolic way, because it is involved in catabolism and anabolism. Cycle occurs, the body needs energy. In addition to provide energy for the body, it provides the intermediate metabolite biosynthesis process.
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